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aldehyde dehydrogenase


Aldehyde dehydrogenases (ALDHs), found in all living organisms from Archaea and Eubacteria to eukaryotes, are a large group of polymorphic enzymes that can catalyze the oxidation of aldehydes to carboxylic acids, which leave the liver and are metabolized by the body’s muscle and heart. ALDH also refers to long-chain-aldehyde dehydrogenases, which is encoded by ALDH3 and involved in the removal of toxic aldehyde generated by alcohol metabolism and lipid peroxidation.

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